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Cardiovascular health; Homocysteine metabolism; Brain and nerve health; Energy metabolism; Red blood cell support
Adults who want convenient methylated B support for daily metabolism and those with low dietary intake of leafy greens or animal-based B12 sources.
Take 1 capsule daily, preferably with a meal; morning use may suit those who feel energized by B vitamins.
Non-GMO; Gluten Free
As the active form of folate, it donates methyl groups for one-carbon metabolism, supporting homocysteine remethylation and DNA synthesis.
Caution: High folate intake may mask signs of low vitamin B12; consider consistent B12 intake if using folate regularly.
Methylcobalamin serves as a cofactor for methionine synthase, helping convert homocysteine to methionine and supporting red blood cell formation and nerve function.
Caution: Very high B12 doses are generally well tolerated, but those with B12-sensitive acne may notice breakouts; take earlier in the day if sensitive to energy effects.
Methylfolate provides methyl groups while methylcobalamin functions as a key cofactor in the same methylation cycle, working together to support homocysteine recycling. Folate supports nucleotide synthesis, and B12 supports red blood cell maturation and neurologic function, creating complementary coverage for cellular metabolism.
Label Warning: Do not exceed the recommended dose. Do not use if the outer seal is broken or damaged. Consult a physician before use if you are being treated for a medical condition or if you are pregnant or lactating.
Who should be cautious: People on medications for seizures or mood, or with B12 or folate metabolism concerns may wish to discuss use with a healthcare provider before starting.
Storage: Store tightly closed in a cool, dry place.
Many users report feeling more energized and balanced after taking the active folate and B12.
Reviewers mention good bioavailability and a small capsule that is easy to take.
A few comments suggest results can differ based on personal needs, such as methylation differences.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Vitamin B12 and Methylfolate may support energy production and red blood cell formation, working together to maintain healthy homocysteine levels.
AI generated. Not medical advice.
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What Is BioActive Folate & Vitamin B12?
BioActive Folate & Vitamin B12 supports the heart, brain, GI tract and more because its capsules contain the clinically studied, biologically active forms of folate (as 5-methyltetrahydrofolate) and vitamin B12 (as methylcobalamin).
BioActive Folate & Vitamin B12 capsules use clinically studied forms of folate and vitamin B12 to maximize benefits.
BioActive Folate & Vitamin B12 Benefits
Read the entire label and follow the directions carefully prior to use.
Take one (1) capsule daily, or as recommended by a healthcare practitioner.
Microcrystalline cellulose, vegetable cellulose (capsule), dicalcium phosphate, .
Store tightly closed in a cool, dry place.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Vegetarian Capsule | ||
| Amount Per Serving | % Daily Value | |
| Folate (as L-5-Methyltetrahydrofolate calcium salt) | 680 mcg° | 170% |
| Vitamin B12 (as methylcobalamin) | 300 mcg | 12,500% |
| °DFE (dietary folate equivalents) | ||
